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Daybue is supplied as a compare avapro and atacand strawberry-flavored oral solution containing 200 mg of trofinetide per mL. The dosage is determined by patient weight and can be administered orally or via gastrostomy tube. The dosage is determined by patient weight and can be administered orally or via gastrostomy tube. A calibrated compare avapro and atacand measuring device (eg, oral syringe, oral dosing cup) should be obtained from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study (ClinicalTrials.

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The most common adverse reactions reported with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints). Findings showed that treatment with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints). The product, compare avapro and atacand which received FDA approval in March 2023, was approved based on data from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study (ClinicalTrials. Having a therapy that has been shown to address multiple symptoms of Rett syndrome provides a promising treatment option that may lead to meaningful impact for patients and their families.

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I am thrilled to now be able to offer Daybue to more people living with Rett syndrome, outside of a clinical trial.

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